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Heart rhythm and rate control by genes and cells.

Our research seeks to understand how the heart rhythm is generated and conducted to pace the entire heart. We translate our mechanistic insights toward clinical therapies with the goal of developing biological agents to treat cardiac arrhythmias.

 

Contact

➤ LOCATION

Department of Pediatric Cardiac Surgery

Blalock-Thomas-Taussig Pediatric and Congenital Heart Center

Johns Hopkins School of Medicine

680 North Wolfe Street.
Baltimore, MD 21205

☎ CONTACT

hcho21@jh.edu
(410) 955-5438


 
A single gene can convert cardiac muscle to pacemaker tissue.
— Hee Cheol Cho

Areas of Research


Congenital heart disease


human pluripotent stem cell engineering


cardiac conduction defects


Somatic cell reprogramming


biological pacemakers


small and large animal models of bradycardia


 

Target patients for BioPacers

CAVB and Sinus Node Dysfunction

Congenital heart disease patients

TAVR-induced condution disorders

Applications

Bridge-to-device

Device replacement

 

 
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